La literatura de cordel es un género literario popular con raíces en el nordeste brasileño. Con el propósito de desarrollar metodologías participativas, en el contexto de una asignatura en el postgrado stricto sensu en Salud Colectiva, se elaboró un folleto inspirado en la obra “A Elite do Atraso: da escravidão a lava-jato” del sociólogo brasileño Jessé Souza. El objetivo fue presentar los capítulos del libro en forma de recital, utilizando la literatura de cordel, para discusión del tema de forma dinámica en espacios de producción de conocimiento en los campos de la educación y de la salud. La obra construida retrata, de forma crítica, la construcción histórica de Brasil por medio de su cuna, con base en las injusticias sociales traídas por los colonizadores, formulada por la esclavitud que hoy día reverbera de forma actualizada en la crisis política, económica y de clases.

A literatura de cordel é um gênero literário popular com raízes no Nordeste brasileiro. Com o propósito de desenvolver metodologias participativas, no contexto de uma disciplina na Pós-Graduação stricto sensu em Saúde Coletiva, elaborou-se um folheto inspirado na obra “A Elite do Atraso: da escravidão à lava-jato” do sociólogo brasileiro Jessé Souza. O objetivo foi apresentar os capítulos do livro em forma de recital, utilizando a literatura de cordel, para discussão do tema de forma dinâmica em espaços de produção de conhecimento nos campos da Educação e da Saúde. A obra construída retrata, de forma crítica, a construção histórica do Brasil mediante seu berço, pautada nas injustiças sociais trazidas com os colonizadores, formuladas pela escravidão que hoje reverbera de forma atualizada nas crises política, econômica e de classes.

Cordel literature is a popular literary genre with roots in the northeast of Brazil. With the aim of developing participatory methodologies for a subject on a Master’s degree in Public Health, we produced a pamphlet inspired by the book “A Elite do Atraso: da escravidão a lava-jato” (The Elite of Backwardness: from slavery to the car wash scandal), by Brazilian sociologist Jessé Souza. The aim of the pamphlet was to present each of the chapters of the book in the form of a recital using cordel literature to promote dynamic discussion of the theme in spaces of knowledge production in the fields of health and education. The pamphlet critically depicts the historic construction of Brazil from the cradle, grounded on social injustice brought by the colonizers and shaped by slavery, which continues to reverberate today, reframed through the political, economic and class crisis.

Abstract Background Juvenile Dermatomyositis (JDM) is the most common idiopathic inflammatory myopathy in children. Imaging exams are useful for muscle assessment, with ultrasonography (US) being a promising tool in detecting disease activity and tissue damage. There are few studies about muscle elastography. Objectives Our aim was to associate clinical, laboratory, and nailfold capillaroscopy (NC) assessments with US in JDM patients; and to compare the findings of US and Strain Elastography (SE) from patients and healthy controls. Methods An analytic cross-sectional study was performed with JDM patients and healthy controls. Patients underwent clinical exam to access muscle strength and completed questionnaires about global assessment of the disease and functional capacity. Patients were submitted to NC and measurement of muscle enzymes. All subjects underwent US assessment, using gray scale, Power Doppler (PD), and SE. Results Twenty-two JDM patients and fourteen controls, aged between 5 and 21 years, matched for age and sex were assessed. In qualitative and semi-quantitative gray scale, we observed a higher frequency of alterations in patients (p < 0.001), while in PD, there was a higher frequency of positivity in patients’ deltoids and anterior tibialis (p < 0.001). Active disease was associated with an important change in the semi-quantitative gray scale in deltoids (p = 0.007), biceps brachii (p = 0.001) and quadriceps femoris (p = 0.005). The SE demonstrated a high negative predictive value of 87.2. Conclusion US was able, through gray scale, to differentiate JDM patients from controls, while PD achieved such differentiation only for deltoids and anterior tibialis. The semi-quantitative gray scale showed disease activity in proximal muscles. SE was not able to differentiate patients from controls.

Ouratea fieldingiana is a native medicinal plant from Northeastern Brazil and many biological properties are due to the phenolic constituents. The objective of this work was performing the characterization of O. fieldingiana leaf constituents to correlate with antioxidant and anticholinesterase activities by in vitro and in silico studies and thus contribute to find new agents against Alzheimer’s disease. The high-performance liquid chromatography revealed the presence of the flavonoids rutin, isoquercitrin, kaempferol-3-O-rutinoside, quercetin, apigenin and amentoflavone. The antioxidant activities by the (2,2-diphenyl-1-picrylhydrazyl) (DPPH) and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) methodologies, showed good results with half maximal inhibitory concentration (IC50) values ranging from 5.63 to 11.47 µg mL-1 and 2.72 to 23.71 µg mL-1, respectively. Acetylcholinesterase inhibition assay pointed out the flavone apigenin with best activity. Computational studies evaluated the interaction of flavonoids with the enzyme acetylcholinesterase co-crystallized with the galantamine, used as standard. All flavonoids exhibited binding energy greater than that of galantamine, but only apigenin showed strong interaction with the active site of the enzyme and other bind probably to different allosteric centers. Then, O. fieldingiana extract and flavonoids with good anti-radical activity and presenting a broad-spectrum action against acetylcholinesterase (AChE) enzyme ought to be tested in clinical studies to discover new neuro-therapeutic candidates.

Abstract As the consideration of soil-structure interaction is increasingly being incorporated into design practice, there is a need for solutions that consider the most relevant aspects of the behaviour of both the concrete and the soil, some of which are time-dependent. The present work introduces a model that suits both the structure and the foundation – including the supporting soil – allowing the coupled analysis of hardening on cure, creep, shrinkage and cracking of concrete, and consolidation of soil. Both the structure and the foundation are modeled as one-dimensional finite elements. The time-dependent behaviour of the concrete and soil is modeled using Kelvin chains. For the structural elements, a mixed finite element formulation is used. Validation tests were conducted in the proposed modeling, comparing its results with available experimental and analytical data. The study of a reinforced concrete continuous beam supported by foundations on consolidating clay considering the time-dependent behaviour of the materials showed considerable changes in the effects of the soil-structure interaction.

Abstract The development of new environmentally-friendly cutting fluids is an important technological advancement. The aim of this study was to assess the tribological behavior of microemulsions (W/O) developed with epoxidized soybean oil and nonionic surfactants with different degrees of ethoxylation (NP4EO, NP6EO and NP9.5EO). The tribological performance of the microemulsion systems was assessed in a High Frequency Reciprocating Rig (HFRR) tribometer. Microemulsions showed Newtonian fluid behavior, with viscosities compatible with conventional cutting fluids. In addition, contact angle values above 90º indicate spherical-shaped drops on the surface on which they are deposited, due to their hydrophobic nature. The microemulsions formulated using surfactants with lower ethoxylation numbers and 20% concentration exhibited greater stability, lower viscosity and better friction reduction during tribological contact between surfaces, given that the average wear scar diameter was 118 µm with smooth surfaces exhibiting slight slippage wear caused by abrasion, as identified by SEM/EDS analyses.

Abstract Objective: This study aims to present standard reference for values of maximum respiratory pressures of healthy schoolchildren, according to gender. Methods: This is a cross-sectional study involving healthy children aged 7–10 years. Data of body mass and height were evaluated to calculate body mass index (BMI). In addition, forced expiratory volume in 1 second (FEV1) and maximal expiratory pressure values were evaluated according to the American Thoracic Society. The maximal inspiratory pressure (MIP) and data of maximal expiratory pressure (MEP) obtained in the study showed normal distribution and curves were built by the Lambda–Mu–Sigma (LMS) method, as well as the values of MIP and MEP percentiles 3, 10, 25, 50, 75, 90, and 97 for each gender. Results: MIP and MEP data were collected from 399 schoolchildren. All schoolchildren in the sample had adequate FEV1 and BMI. The study showed an increase in respiratory pressure values with age progression. The MIP and MEP values of girls were of 53.4±11.0 and 61.8±12.5cmH2O, respectively, and those of boys were 59.9±13.6 and 69.6±15.7cmH2O, respectively. Conclusions: Normal curves and percentiles were developed for MIP and MEP values of healthy schoolchildren. The extreme percentiles (3rd and 97th) were determined, and a specific graph was elaborated for each group. These graphs may help clinical follow-up and therapeutic monitoring of different pediatric populations.

Resumo Objetivo: Apresentar distribuição normal para os valores das pressões respiratórias máximas de escolares saudáveis, de acordo com o gênero. Métodos: Estudo transversal envolvendo crianças saudáveis de 7 a 10 anos. Foram avaliados os dados de massa corporal e estatura, para o cálculo do índice de massa corporal (IMC). Os valores de volume expiratório forçado no primeiro segundo (VEF1) e pressão expiratória máxima foram avaliados de acordo com a American Thoracic Society. Os dados de pressão inspiratória máxima (PImáx) e pressão expiratória máxima (PEmáx) obtidos no estudo deram origem à distribuição normal, cuja construção foi elaborada pelo método the Lambda-Mu-Sigma (LMS), bem como os percentis 3, 10, 25, 50, 75, 90 e 97 de PImáx e PImáx de cada sexo. Resultados: Os dados de PImáx e PImáx foram coletados de 399 escolares. Todos os escolares da amostra apresentavam VEF1 e índice de massa corporal adequados. O estudo mostrou aumento dos valores de pressão respiratória com o avançar da idade. Os valores de PImáx e PImáx das meninas foram de 53,49±11,07 e 61,80±12,51cmH2O, respectivamente; e os meninos de 59,96±13,66 e 69,68±15,72 cmH2O, respectivamente. Conclusões: Foram desenvolvidas curvas e percentis normais para os valores de PImáx e PImáx de escolares saudáveis o que poderia auxiliar no acompanhamento clínico e terapêutico de diferentes populações pediátricas.

Abstract The log of a SPT in very soft clay may simply indicate a zero blow-count, or present information on the penetration – under self-weight – of the composition (sampler, rods and hammer) as recommended by some standards. The second type of information is often disregarded by design engineers due to the lack of a standard procedure for measuring these penetrations or because the test is regarded as not sensitive enough to give an indication on the undrained shear strength of soft clays. The penetration under the composition’s self-weight, however, can indicate the magnitude of Su, which, along with other more specific and sensitive tests, can help in assessing the spatial distribution of clay consistency in a large deposit. A proposed test procedure and interpretation had been given in an earlier technical note. This note presents an extended formulation and an evaluation of Su via the SPT at a construction site in Rio de Janeiro, including comparisons with results of piezocone and vane tests. The values of Su obtained with the SPT lie between the profiles given by vane tests, corrected by Plasticity Index, and the Critical State Theory, the latter representing a lower bound to the clay strength.

Resumo A estequiometria é um dos conteúdos de Química que necessariamente recorre aos conceitos matemáticos para resoluções de problemas. A necessidade de realizar transformações de unidade, a relação molar de reagentes e produtos de uma reação requer a capacidade de operacionalizar a adição, subtração, multiplicação ou divisão. Assim, compreendendo a existência dessa inter-relação entre a Matemática e a Química, objetiva-se neste estudo apresentar a importância da abordagem interdisciplinar entre ambas as áreas no processo de ensino-aprendizagem por meio da resolução de questões de estequiometria do ENEM. Metodologicamente, o trabalho se constitui a partir de uma pesquisa bibliográfica exploratória, na qual foram revisadas as questões de Química das últimas cinco edições do ENEM. Após a identificação, selecionaram-se questões de estequiometria para resolução, de modo a compreender a importância dos conhecimentos da Matemática para tais situações. Assim, constatou-se que ao longo dos cinco anos 18,5% das perguntas de Química necessitam de conhecimentos matemáticos, entre essas, 45% são questões de estequiometria. Portanto, partindo das constatações observadas nas questões, compreende-se que é indispensável à abordagem interdisciplinar nos processos de ensino-aprendizagem, sobre tudo no ensino de estequiometria, de modo que os discentes tenham a capacidade de aplicar alguns conceitos matemáticos em problemas envolvendo a Química.

Abstract Stoichiometry is one of the contents of Chemistry that necessarily uses mathematical concepts to solve problems. The need to perform unit transformations, the molar ratio of reagents and products of a reaction requires the ability to operationalize addition, subtraction, multiplication or division. Thus, understanding the existence of this interrelation between Mathematics and Chemistry, the objective of this study is to present the importance of the interdisciplinary approach between both areas in the teaching-learning process through the resolution of issues of stoichiometry of ENEM. Methodologically, the work is based on an exploratory bibliographic research, in which the Chemistry questions from the last five editions of ENEM were reviewed. After identification, stoichiometry questions were selected for resolution, in order to understand the importance of mathematical knowledge for such situations. Thus, it was found that over the five years, 18.5% of Chemistry questions require mathematical knowledge, among which, 45% are stoichiometric questions. Therefore, based on the findings observed in the questions, it is understood that it is essential to the interdisciplinary approach in the teaching-learning processes, especially in the teaching of stoichiometry, so that students have the ability to apply some mathematical concepts in problems involving Chemistry.

Abstract This note presents an alternative method for static load tests on piles (and caissons). Called Equilibrium Method by its first proponents, the method was applied in some load tests in Brazil, in addition to being the object of theoretical studies conducted at the Federal University of Rio de Janeiro. The method consists, in each step, to keep the load constant for a period of time and then let it relax (not pumping the jack) until the displacement and the load reach mutual equilibrium. The stabilized displacement and the relaxed load (the so-called load and displacement in equilibrium) are considered for the load-displacement curve. The method has the advantage of producing the load-displacement curve close to that of a slow, stabilized test (incremental slow maintained load test), but with a shorter total execution time. The paper includes a short theoretical background and a review of the Brazilian experience.

Abstract Dynamic formulae are a widely used expedient for the control of driven piles to ensure load capacity. These formulae have considerable limitations when used in the prediction of the load capacity on their own, but are very useful in the control of a piling when combined with other tests. This technical note presents an evaluation of the Danish Formula for 54 precast concrete piles, comparing its results with High Strain Dynamic Tests (HSDTs), Static Load Tests (SLTs) and predictions by a semi-empirical static method (Aoki & Velloso, 1975). The data used in the comparison come from three works in the city of Rio de Janeiro, Brazil. All piles were driven with free-fall hammers and in one particular work the piles were relatively short. The predictions of the Danish Formula were evaluated in relation to the pile length/diameter ratio. It was concluded that for short piles - with lengths less than 30 times the diameter - this formula indicates bearing capacities higher than the actual ones. A correction for a safe use of the Danish Formula for short piles is suggested.

RESUMO Objetivo: Verificar as repercussões do teste de esforço submáximo na mecânica respiratória e na função pulmonar de escolares. Métodos: Estudo transversal com escolares de 7 a 14 anos submetidos à avaliação da mecânica respiratória por sistema de oscilometria de impulso (IOS) e da função pulmonar pela espirometria. Realizou-se também o teste de caminhada de seis minutos (TC6), todos segundo os padrões da Sociedade Torácica Americana. O TC6 foi executado duas vezes com intervalo de 30 minutos entre cada teste. O IOS e a espirometria foram feitos antes do primeiro TC6 (pré-TC6) e repetidos imediatamente após o primeiro TC6 (pós-TC61) e após o segundo TC6 (pós-TC62). A comparação dos resultados nos três tempos do estudo se deu por análise de variância para medidas repetidas (teste post-hoc de Bonferroni) ou teste de Friedman, sendo significante p≤0,05. Resultados: Participaram 21 sujeitos; 53% masculinos e idade média de 10,9±2,3 anos. Encontraram-se diferenças entre resistência total (R5) e resistência central das vias aéreas (R20) nos 3 tempos do estudo (p=0,025 e p=0,041, respectivamente). A análise post-hoc indicou aumento de resistência R5 entre pré-TC6 e pós-TC61 (R5=0,540±0,100 versus 0,590±0,150 kPa/L/s, p=0,013; e R20=0,440±0,800 versus 0,470±0,100 kPa/L/s, p=0,038). A única variável espirométrica com alteração no decorrer do tempo foi o fluxo expiratório forçado 25-75% (FEF25-75%) (p=0,003). Conclusões: As repercussões encontradas foram: aumento da resistência total e da resistência central das vias aéreas e redução do FEF25-75% após o TC6 em escolares, sugerindo a necessidade de mais atenção na realização de testes submáximos em crianças com alguma predisposição a alterações das vias aéreas.

ABSTRACT Objective: To verify repercussions of submaximal exercise testing on respiratory mechanics and pulmonary function in schoolchildren. Methods: Cross-sectional study, with children aged 7 to 14 years, who had their respiratory mechanics assessed by impulse oscillometry (IOS), and pulmonary function by spirometry. They performed the six-minute walk test (6MWT), as per the standards by the American Thoracic Society. The 6MWT was performed twice with a 30-minute interval. IOS and spirometry were performed before the first 6MWT (Pre-6MWT) and immediately after the first (Post-6MWT1) and second walking tests (Post-6MWT2). The results in these three phases were compared by analysis of variance for repeated measures (post-hoc Bonferroni test) or by the Friedman’s test, with p≤0.05 considered significant. Results: Twenty-one subjects participated in the study: 53% were males and mean age was 10.9±2.3 years. There were differences between total resistance (R5) and central airway resistance (R20) at the three phases of assessment (p=0.025 and p=0.041, respectively). Post-hoc analysis indicated increase in R5 when Pre-6MWT and Post-6MWT1 were compared (R5=0.540±0.100 versus 0.590±0.150 kPa/L/s, p=0.013; and R20=0.440±0.800 versus 0.470±0.100 kPa/L/s, p=0.038). Forced expiratory flow 25-75% (FEF25-75%) changed over time (p=0.003). Conclusions: Repercussions were: increase in central and total airway resistance and reduction of FEF25-75% after 6MWT in schoolchildren, suggesting that greater attention should be given to submaximal tests in children with predisposition to airways alterations.

RESUMO: Objetivando determinar a prevalência de anticorpos anti-Trypanosoma vivax e os possíveis fatores de risco associados à infecção em bovinos no estado do Rio Grande do Norte, nordeste do Brasil, o trabalho consistiu em um estudo epidemiológico transversal, com amostragem não probabilística por conveniência, no qual foram analisadas, por meio da reação de imunofluorescência indireta, 467 amostras de soro sanguíneo de bovinos. Das amostras testadas, 42 foram reagentes para anticorpos IgG anti-Trypanosoma vivax, o que correspondeu à prevalência de 9,0%. Os fatores de risco que influenciaram a ocorrência da tripanossomose foram: exploração com finalidade do tipo leite, criação de bovinos de raça europeia, categoria animal vaca em lactação, aquisição de animais, forrageamento das margens de açudes e rios, além da presença de vetores mecânicos. A alta prevalência encontrada em animais de corte (59,5%), fêmeas (95,2%), raça europeia (88,1%), vacas em lactação (85,7%), pastagem a margens de açudes e rios (95,2%), além da presença de vetores mecânicos (81%) e aquisição de animais (88,1%), indica a expansão da tripanossomose no semiárido do Nordeste, e as informações obtidas poderão esclarecer os fatores epidemiológicos que determinam a ocorrência da tripanossomose por T. vivax na região.

ABSTRACT: The objective of this study was to determine the prevalence of anti Trypanosoma vivax antibodies and the possible risk factors associated with the infection in cattle in Rio Grande do Norte, Northeastern Brazil, through a cross-sectional epidemiological study, with non-probabilistic convenience sampling. A total of 467 cattle’s serum samples were analyzed by indirect immunofluorescence. Forty-two samples tested positive for Trypanosoma vivax IgG antibodies, corresponding to the prevalence of 9%. Risk factors influencing the occurrence of trypanosomiasis were milk exploration, raising of European breeds, productivity category: lactation cow, purchase of new cattle, foraging habits near ponds and rivers, and the presence of mechanical vectors. So, high prevalence in beef animals (59.5%), females (95.2%), European breed (88.1%), lactating cows (85.7%), pasture at banks of dams and rivers (95.2%), in addition to the presence of mechanical vectors (81%) and acquisition of animals (88.1%), indicates the expansion of trypanosomiasis in Northeastern semi-arid region, and the information obtained may explain the epidemiological factors that determine the occurrence of trypanosomiasis by T. vivax in this region.

ABSTRACT Folic acid is a B complex water-soluble vitamin that is essential to humans, and its deficiency can cause problems including congenital malformations in the fetus as well as heart disease. Most countries affected by diseases associated with a lack of folic acid now supplement foods with the vitamin. There is therefore a need for the development of new analytical procedures able to determine folic acid present in different matrices. This work describes the development of zero order and first order derivative spectrophotometric methods for the determination of folic acid in different pharmaceutical formulations, using 0.1 mol L-1 NaOH as solvent. The methods are shown to be simple, selective, and robust. Good linearity was achieved, with correction coefficients ≥0.9996 and limits of detection and quantification ranging from 0.64 to 0.75 and from 1.80 to 2.85 mg L-1, respectively. Recoveries of 98-104% were obtained in accuracy tests, and precision (as RSD) was between 0.2 and 4.8%. The methods can be used in routine analyses for quality control purposes, offering an alternative to the procedures already reported in the literature.

Resumo A partir de 1998 com a criação do Sistema Financeiro Imobiliário (SFI), o setor imobiliário brasileiro passou por mudanças estruturais. Dentre as principais está a forte capitalização das grandes incorporadoras mediante a abertura de capitais em bolsa de valores o que permitiu a expansão da incorporação imobiliária por todo território brasileiro. Regiões brasileiras que historicamente tiveram baixo preço do m2 e demanda solvável reduzida passaram a receber novos empreendimentos, até mesmo em áreas periféricas e carentes de infraestrutura, evidenciando uma suburbanização. Assim, a compreensão da urbanização enquanto economia política do espaço permite analisar a proximidade cada vez mais tênue entre espaço urbano e capital financeiro, bem como os fetiches envolvidos.

Abstract With the creation of the Real Estate Financing System (SFI) in 1998, the real estate sector in Brazil underwent structural changes. Among the main ones is the strong capitalization of the big developers through the initial public offering on the stock market which allowed the expansion of the real estate development throughout Brazil. Brazilian regions that have historically had low price of land per m2 and reduced solvable demand started to receive new ventures, even in peripheral areas with deficient infrastructure, showing suburbanization. Thus, an understanding of urbanization as a political economy of space allows an analysis of the increasingly tenuous proximity between urban space and financial capital, as well as the fetishes involved.

Resumen A partir de 1998 con la creación del Sistema Financeiro Imobiliário (SFI), el sector inmobiliário brasileño experimentó cambios estructurales. Entre los más importantes está la fuerte capitalización de los grandes desarolladores abriendo el capital en bolsa de valores que permitió la expansión de la incorporación en todo Brasil. Regiones del país que históricamente han tenido bajo precios del m2 y la reducción de la demanda resoluble comenzaron a recibir nuevas empresas, incluso en zonas periféricas con infraestructura deficiente, lo que evidencia una suburbanización. Por lo tanto, la comprensión de la urbanización como economía política del espacio nos permite analizar la cercanía cada vez más borrosa entre el espacio urbano y el capital financeiro, así como los fetiches involucrados.